RANK which is also referred to as TRANCE receptor (TNFSF11), is a specific type I membrane protein which is mainly expressed on the surfaces of osteoclasts and is responsible for their activation following binding to the ligand. It is found to consist of 383 amino acids in its intracellular domain (from residues 234-616), also containing three putative TRAF-binding domains that are termed I, II, and III.

ELISA kit information:

• Reactivity: Human
• Sample Type: Serum, Tissue Homogenates, Various Biological Fluids, Plasma
• Sensitivity: 46.875 pg/ml
• Target: RANK, Receptor Activator Of Nuclear Factor Kappa B, TNFSF11, TRANCE Receptor