ICTP, or cross-linked C-telopeptide of type I collagen, constitutes a peptide degradation product generated by osteoclastic resorption of mature, crosslinked collagen type I fibrils that make up the bone matrix. As bone tissue undergoes constant turnover mediated by opposing activity of osteoblasts and osteoclasts, biomarkers of the coordinated remodeling process provide critical insight into prevailing bone balance in research and clinical contexts.

ELISA kit information:

• Reactivity: Human
• Sample Type: Plasma, Tissue Homogenates, Serum, Biological Fluids
• Sensitivity: 46.875 pg/ml
• Target: C-Terminal Telopeptide Of Collagen Alpha-1, ICTP