Fractalkine, officially termed CX3CL1, represents a unique chemokine known to mediate adhesion and migration in both soluble and membrane-anchored forms. Its identification emerged in 1997 when a cDNA library screen uncovered a novel protein containing a CX3C chemokine domain, an extended mucin-like stalk, and transmembrane helix – yielding exceptional capability to exist either bound or shed from membranes.

ELISA kit information:

• Reactivity: Human
• Sample Type: Plasma, Tissue Homogenates, Serum, Biological Fluids
• Sensitivity: 75 pg/ml
• Target: Chemokine C-X3-C-Motif Ligand 1, Fractalkine