Caspase-1 sits at the crux of inflammatory processes as the essential enzymatic executor enabling cytokine maturation and pyroptotic cell death – two cardinal responses against pathogens. First described in 1996 as the founder of inflammatory caspases, it took years of ensuing research to reveal mechanistic details underlying its influential role marshalling anti-microbial immunity.

ELISA kit information:

• Reactivity: Human
• Sample Type: Plasma, Tissue Homogenates, Serum, Biological Fluids
• Sensitivity: 46.875 pg/ml
• Target: CASP1, Caspase-1, ICE, CASP-1, ICEP45