Menu

Alpha-Lactalbumin (LALBA): A Multifunctional Protein in Lactation and Beyond

Endocrinology Diagnostics

Introduction:

  • LALBA is a prominent whey protein in milk
  • Contains 123 amino acids
  • Essential for lactose production
  • Has multiple biological functions including antimicrobial and immunomodulatory effects

Structure and Function:

  • Member of α-lactalbumin protein group
  • Structure includes tightly folded amino acid chain
  • Held together by disulfide bonds
  • Three-dimensional shape crucial for binding and lactose production regulation

Lactose Synthesis:

  • Partners with β-1,4-galactosyltransferase (β-GalT)
  • Facilitates galactose to glucose conversion
  • Essential for lactose production
  • Maintains milk osmotic balance
  • Supports nutrient absorption

Role in Infant Nutrition:

  • Makes up 25% of whey proteins in breast milk
  • Easily absorbed and digested
  • Provides essential amino acids for infant growth
  • Promotes gut health
  • Supports immune system development
  • Helps establish healthy gut microbiome

Cancer Research:

  • Shows potential anti-cancer properties
  • Can inhibit growth of specific cancer cells
  • May trigger cell death in breast cancer cells
  • Affects cell signaling pathways related to growth and survival

Nutraceuticals and Food Industry:

  • Used in dairy products and protein supplements
  • Adds nutritional value to food products
  • Popular in health-focused foods
  • Promotes general wellness

Future Directions and Research:

  • Investigating effects on obesity and inflammatory diseases
  • Research on extraction and refinement methods
  • Development of high-quality supplements
  • Potential for engineered production processes
  • Focus on increasing accessibility for research and commercial use
ENQUIRY FORM

More News

  • TNF Alpha: A Central Mediator of Inflammation and Immune Response

  • Sclerostin (SOST): The Master Regulator of Bone Formation

  • TNFSF11/RANKL: A Key Regulator of Bone Metabolism and Beyond

  • Superoxide Dismutase (SOD): The Body's Powerful Antioxidant Defence System